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CRISPR-Cpf1-Assisted Multiplex Genome Editing and Transcriptional Repression in Streptomyces

Streptomyces has a strong capability for producing a large number of bioactive natural products and remains invaluable as a source for the discovery of novel drug leads. Although the Streptococcus pyogenes CRISPR-Cas9-assisted genome editing tool has been developed for rapid genetic engineering in S...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Li, Lei, Wei, Keke, Zheng, Guosong, Liu, Xiaocao, Chen, Shaoxin, Jiang, Weihong, Lu, Yinhua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6121969/
https://ncbi.nlm.nih.gov/pubmed/29980561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00827-18
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