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Multiplexed CRISPR technologies for gene editing and transcriptional regulation

Multiplexed CRISPR technologies, in which numerous gRNAs or Cas enzymes are expressed at once, have facilitated powerful biological engineering applications, vastly enhancing the scope and efficiencies of genetic editing and transcriptional regulation. In this review, we discuss multiplexed CRISPR t...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: McCarty, Nicholas S., Graham, Alicia E., Studená, Lucie, Ledesma-Amaro, Rodrigo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062760/
https://ncbi.nlm.nih.gov/pubmed/32152313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15053-x
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