Antibody to Marinobufagenin Reverses Placenta-Induced Fibrosis of Umbilical Arteries in Preeclampsia

Background: Previous studies implicated cardiotonic steroids, including Na/K-ATPase inhibitor marinobufagenin (MBG), in the pathogenesis of preeclampsia (PE). Immunoneutralization of heightened MBG by Digibind, a digoxin antibody, reduces blood pressure (BP) in patients with PE, and anti-MBG monoclo...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Fedorova, Olga V., Ishkaraeva, Valentina V., Grigorova, Yulia N., Reznik, Vitaly A., Kolodkin, Nikolai I., Zazerskaya, Irina E., Zernetkina, Valentina, Agalakova, Natalia I., Tapilskaya, Natalia I., Adair, C. David, Lakatta, Edward G., Bagrov, Alexei Y.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6121256/
https://ncbi.nlm.nih.gov/pubmed/30104471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19082377
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