Up-Regulation of TLR7-Mediated IFN-α Production by Plasmacytoid Dendritic Cells in Patients With Systemic Lupus Erythematosus

Objectives: Aberrant and persistent production of interferon-α (IFN-α) by plasmacytoid dendritic cells (pDCs) is known to play a key role in the pathogenesis of systemic lupus erythematosus (SLE). To assess the precise function of pDCs in SLE patients, we investigated the differential regulation of...

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發表在:Front Immunol
Main Authors: Sakata, Kei, Nakayamada, Shingo, Miyazaki, Yusuke, Kubo, Satoshi, Ishii, Akina, Nakano, Kazuhisa, Tanaka, Yoshiya
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2018
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6121190/
https://ncbi.nlm.nih.gov/pubmed/30210502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01957
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