Janus Kinase Inhibitor Baricitinib Modulates Human Innate and Adaptive Immune System

The purpose of this study was to elucidate the mechanism of action of baricitinib on Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling, which involves in human innate and adaptive immune system. The effects of baricitinib were evaluated using human monocyte-derived...

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Detalles Bibliográficos
Publicado en:Front Immunol
Autores principales: Kubo, Satoshi, Nakayamada, Shingo, Sakata, Kei, Kitanaga, Yukihiro, Ma, Xiaoxue, Lee, Seunghyun, Ishii, Akina, Yamagata, Kaoru, Nakano, Kazuhisa, Tanaka, Yoshiya
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031708/
https://ncbi.nlm.nih.gov/pubmed/30002661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01510
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