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Critical roles of super-enhancers in the pathogenesis of autoimmune diseases

The super-enhancer (SE) is a cluster of enhancers involved in cell differentiation via enhanced gene expression that determines cell identity. Meanwhile, genome-wide association studies (GWASs) have reported the presence of gene clusters containing single nucleotide polymorphisms (SNPs) susceptible...

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Bibliographic Details
Published in:Inflamm Regen
Main Authors: Yamagata, Kaoru, Nakayamada, Shingo, Tanaka, Yoshiya
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398324/
https://ncbi.nlm.nih.gov/pubmed/32922569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41232-020-00124-9
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