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BAFF- and APRIL-targeted therapy in systemic autoimmune diseases

B cells play a pivotal role in autoimmunity not only by producing pathogenic autoantibodies but also by modulating immune responses via the production of cytokines and chemokines. The B cell-activating factor/a proliferation-inducing ligand (BAFF/APRIL) system promotes B cell survival and differenti...

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Bibliografiske detaljer
Udgivet i:Inflamm Regen
Main Authors: Nakayamada, Shingo, Tanaka, Yoshiya
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725651/
https://ncbi.nlm.nih.gov/pubmed/29259679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41232-016-0015-4
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