Chimeric Proteins Containing MAP-1 and Functional Domains of C4b-Binding Protein Reveal Strong Complement Inhibitory Capacities

The complement system is a tightly regulated network of proteins involved in defense against pathogens, inflammatory processes, and coordination of the innate and adaptive immune responses. Dysregulation of the complement cascade is associated with many inflammatory disorders. Thus, inhibition of th...

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Vydáno v:Front Immunol
Hlavní autoři: Hertz, Cecilie E., Bayarri-Olmos, Rafael, Kirketerp-Møller, Nikolaj, van Putten, Sander, Pilely, Katrine, Skjoedt, Mikkel-Ole, Garred, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120983/
https://ncbi.nlm.nih.gov/pubmed/30210498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01945
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