C-Reactive Protein Binds to Cholesterol Crystals and Co-Localizes with the Terminal Complement Complex in Human Atherosclerotic Plaques

Inflammation is a part of the initial process leading to atherosclerosis and cholesterol crystals (CC), found in atherosclerotic plaques, which are known to induce complement activation. The pentraxins C-reactive protein (CRP), long pentraxin 3 (PTX3), and serum amyloid P component (SAP) are serum p...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Pilely, Katrine, Fumagalli, Stefano, Rosbjerg, Anne, Genster, Ninette, Skjoedt, Mikkel-Ole, Perego, Carlo, Ferrante, Angela M. R., De Simoni, Maria-Grazia, Garred, Peter
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581807/
https://ncbi.nlm.nih.gov/pubmed/28900428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01040
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