Chimeric Proteins Containing MAP-1 and Functional Domains of C4b-Binding Protein Reveal Strong Complement Inhibitory Capacities

The complement system is a tightly regulated network of proteins involved in defense against pathogens, inflammatory processes, and coordination of the innate and adaptive immune responses. Dysregulation of the complement cascade is associated with many inflammatory disorders. Thus, inhibition of th...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Hertz, Cecilie E., Bayarri-Olmos, Rafael, Kirketerp-Møller, Nikolaj, van Putten, Sander, Pilely, Katrine, Skjoedt, Mikkel-Ole, Garred, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120983/
https://ncbi.nlm.nih.gov/pubmed/30210498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01945
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