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Synthesis of chiral α-trifluoromethyl alcohols and ethers via enantioselective Hiyama cross-couplings of bisfunctionalized electrophiles

Methods for synthesis of chiral organic compounds bearing trifluoromethyl-substituted stereocenters are of great interest for agrochemical and pharmaceutical labs and industries in their search for new bioactive materials. We report on employment of bisfunctionalized electrophiles, bearing both a tr...

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Publicat a:Nat Commun
Autors principals: Varenikov, Andrii, Gandelman, Mark
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120892/
https://ncbi.nlm.nih.gov/pubmed/30177813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05946-3
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