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Signaling pathways and steroid receptors modulating estrogen receptor α function in breast cancer

Estrogen receptor α (ER) is the major driver of ∼75% of breast cancers, and multiple ER targeting drugs are routinely used clinically to treat patients with ER(+) breast cancer. However, many patients relapse on these targeted therapies and ultimately develop metastatic and incurable disease, and un...

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Bibliographic Details
Published in:Genes Dev
Main Authors: Siersbæk, Rasmus, Kumar, Sanjeev, Carroll, Jason S.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120708/
https://ncbi.nlm.nih.gov/pubmed/30181360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.316646.118
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