Progesterone receptor modulates estrogen receptor-α action in breast cancer

Progesterone receptor (PR) expression is employed as a biomarker of estrogen receptor-α (ERα) function and breast cancer prognosis. We now show that PR is not merely an ERα-induced gene target, but is also an ERα-associated protein that modulates its behaviour. In the presence of agonist ligands, PR...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Nature
Auteurs principaux: Mohammed, Hisham, Russell, I. Alasdair, Stark, Rory, Rueda, Oscar M., Hickey, Theresa E., Tarulli, Gerard A., Serandour, Aurelien A. A., Birrell, Stephen N., Bruna, Alejandra, Saadi, Amel, Menon, Suraj, Hadfield, James, Pugh, Michelle, Raj, Ganesh V., Brown, Gordon D., D’Santos, Clive, Robinson, Jessica L. L., Silva, Grace, Launchbury, Rosalind, Perou, Charles M., Stingl, John, Caldas, Carlos, Tilley, Wayne D., Carroll, Jason S.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650274/
https://ncbi.nlm.nih.gov/pubmed/26153859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14583
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires