AKT Alters Genome-Wide Estrogen Receptor α Binding and Impacts Estrogen Signaling in Breast Cancer

Estrogen regulates several biological processes through estrogen receptor α (ERα) and ERβ. ERα-estrogen signaling is additionally controlled by extracellular signal activated kinases such as AKT. In this study, we analyzed the effect of AKT on genome-wide ERα binding in MCF-7 breast cancer cells. Pa...

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Main Authors: Bhat-Nakshatri, Poornima, Wang, Guohua, Appaiah, Hitesh, Luktuke, Nikhil, Carroll, Jason S., Geistlinger, Tim R., Brown, Myles, Badve, Sunil, Liu, Yunlong, Nakshatri, Harikrishna
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593438/
https://ncbi.nlm.nih.gov/pubmed/18838536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00799-08
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