PBRM1 bromodomains variably influence nucleosome interactions and cellular function

Chromatin remodelers use bromodomains (BDs) to recognize histones. Polybromo 1 (PBRM1 or BAF180) is hypothesized to function as the nucleosome-recognition subunit of the PBAF chromatin-remodeling complex and is frequently mutated in clear cell renal cell carcinoma (ccRCC). Previous studies have appl...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Slaughter, Mariesa J., Shanle, Erin K., McFadden, Andrew W., Hollis, Emily S., Suttle, Lindsey E., Strahl, Brian D., Davis, Ian J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2018
Matèries:
Molecular Bases of Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120218/
https://ncbi.nlm.nih.gov/pubmed/29986887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003381
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