Obesity-induced protein carbonylation in murine adipose tissue regulates the DNA-binding domain of nuclear zinc finger proteins

In obesity-linked insulin resistance, oxidative stress in adipocytes leads to lipid peroxidation and subsequent carbonylation of proteins by diffusible lipid electrophiles. Reduction in oxidative stress attenuates protein carbonylation and insulin resistance, suggesting that lipid modification of pr...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Hauck, Amy K., Zhou, Tong, Hahn, Wendy, Petegrosso, Raphael, Kuang, Rui, Chen, Yue, Bernlohr, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2018
Soggetti:
Metabolism
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120186/
https://ncbi.nlm.nih.gov/pubmed/30012885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003469
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