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Obesity-induced protein carbonylation in murine adipose tissue regulates the DNA-binding domain of nuclear zinc finger proteins

In obesity-linked insulin resistance, oxidative stress in adipocytes leads to lipid peroxidation and subsequent carbonylation of proteins by diffusible lipid electrophiles. Reduction in oxidative stress attenuates protein carbonylation and insulin resistance, suggesting that lipid modification of pr...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Hauck, Amy K., Zhou, Tong, Hahn, Wendy, Petegrosso, Raphael, Kuang, Rui, Chen, Yue, Bernlohr, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120186/
https://ncbi.nlm.nih.gov/pubmed/30012885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003469
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