Routine Determination of Ice Thickness for Cryo-EM Grids

Recent advances in instrumentation and automation have made cryo-EM a popular method for producing near-atomic resolution structures of a variety of proteins and complexes. Sample preparation is still a limiting factor in collecting high quality data. Thickness of the vitreous ice in which the parti...

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Udgivet i:J Struct Biol
Main Authors: Rice, William J., Cheng, Anchi, Noble, Alex J., Eng, Edward T., Kim, Laura Y., Carragher, Bridget, Potter, Clinton S.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6119488/
https://ncbi.nlm.nih.gov/pubmed/29981485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2018.06.007
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