CD72/CD100 and PD-1/PD-L1 markers are increased on T and B cells in HIV-1(+) viremic individuals, and CD72/CD100 axis is correlated with T-cell exhaustion

In our work, we analyzed the role of the CD100/CD72 and PD-1/PD-L1 axes in immune response dysfunction in human immunodeficiency virus (HIV)-1 infection in which high expressions of PD-1 and PD-L1 were associated with an immunosuppressive state via limitation of the HIV-1-specific T-cell responses....

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Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Correa-Rocha, Rafael, Lopez-Abente, Jacobo, Gutierrez, Carolina, Pérez-Fernández, Verónica Astrid, Prieto-Sánchez, Adrián, Moreno-Guillen, Santiago, Muñoz-Fernández, María-Ángeles, Pion, Marjorie
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6117071/
https://ncbi.nlm.nih.gov/pubmed/30161254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203419
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