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CD40 Activation Rescues Antiviral CD8(+) T Cells from PD-1-Mediated Exhaustion
The intrahepatic immune environment is normally biased towards tolerance. Nonetheless, effective antiviral immune responses can be induced against hepatotropic pathogens. To examine the immunological basis of this paradox we studied the ability of hepatocellularly expressed hepatitis B virus (HBV) t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3708877/ https://ncbi.nlm.nih.gov/pubmed/23853599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003490 |
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