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CD40 Signaling to the Rescue: A CD8 Exhaustion Perspective in Chronic Infectious Diseases

Chronic infectious diseases such as HIV, HBV, and HCV, among others, cause severe morbidity and mortality globally. Progressive decline in CD8 functionality, survival, and proliferative potential—a phenomenon referred to as CD8 exhaustion—is believed to be responsible for poor pathogen control in ch...

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Detalles Bibliográficos
Main Authors: Bhadra, Rajarshi, Cobb, Dustin A., Khan, Imtiaz A.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051158/
https://ncbi.nlm.nih.gov/pubmed/23971530
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