Comparison of statistical methods and the use of quality control samples for batch effect correction in human transcriptome data

Batch effects are technical sources of variation introduced by the necessity of conducting gene expression analyses on different dates due to the large number of biological samples in population-based studies. The aim of this study is to evaluate the performances of linear mixed models (LMM) and Com...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Espín-Pérez, Almudena, Portier, Chris, Chadeau-Hyam, Marc, van Veldhoven, Karin, Kleinjans, Jos C. S., de Kok, Theo M. C. M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2018
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6117018/
https://ncbi.nlm.nih.gov/pubmed/30161168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202947
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