Exploring the nature of prediagnostic blood transcriptome markers of chronic lymphocytic leukemia by assessing their overlap with the transcriptome at the clinical stage

BACKGROUND: We recently identified 700 genes whose expression levels were predictive of chronic lymphocytic leukemia (CLL) in a genome-wide gene expression analysis of prediagnostic blood from future cases and matched controls. We hypothesized that a large fraction of these markers were likely relat...

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Veröffentlicht in:BMC Genomics
Hauptverfasser: Vlaanderen, Jelle, Leenders, Max, Chadeau-Hyam, Marc, Portengen, Lützen, Kyrtopoulos, Soterios A., Bergdahl, Ingvar A., Johansson, Ann-Sofie, Hebels, Dennie D.G.A.J., de Kok, Theo M.C.M., Vineis, Paolo, Vermeulen, Roel C.H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360061/
https://ncbi.nlm.nih.gov/pubmed/28320322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3627-4
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