A comprehensive evaluation of Hippo pathway silencing in sarcomas

TAZ and YAP are transcriptional coactivators negatively regulated by the Hippo pathway that have emerged as key oncoproteins in several cancers including sarcomas. We hypothesized that loss of expression of the Hippo kinases might be a mechanism of activating TAZ and YAP. By immunohistochemistry, TA...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Merritt, Nicole M., Fullenkamp, Colleen A., Hall, Sarah L., Qian, Qining, Desai, Chandni, Thomason, Jon, Lambertz, Allyn M., Dupuy, Adam J., Darbro, Benjamin, Tanas, Munir R.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6114978/
https://ncbi.nlm.nih.gov/pubmed/30167083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25824
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