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Photodynamic Therapy Using Hippo Pathway Inhibitor Verteporfin: A Potential Dual Mechanistic Approach in Treatment of Soft Tissue Sarcomas

SIMPLE SUMMARY: Advanced sarcomas have yet to undergo improved outcomes seen in other cancer subtypes. Verteporfin has the potential to show landmark change in sarcoma due to its anti-proliferative properties: inhibition of the Hippo pathway and as photodynamic therapy. The effect of verteporfin on...

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Publicat a:Cancers (Basel)
Autors principals: Rytlewski, Jeffrey D., Scalora, Nicholas, Garcia, Keith, Tanas, Munir, Toor, Fatima, Miller, Benjamin, Allen, Bryan, Milhem, Mohammed, Monga, Varun
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7915813/
https://ncbi.nlm.nih.gov/pubmed/33567506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13040675
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