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A Phase I/II Study Targeting Angiogenesis Using Bevacizumab Combined with Chemotherapy and a Histone Deacetylase Inhibitor (Valproic Acid) in Advanced Sarcomas

Epigenetic events and genetic alterations under the control of the tumor microenvironment potentially mediate tumor induced angiogenesis involved in soft tissue sarcoma (STS) metastasis. Addition of antiangiogenic agent, such as bevacizumab, to standard chemotherapy in treatment of sarcoma has been...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Monga, Varun, Swami, Umang, Tanas, Munir, Bossler, Aaron, Mott, Sarah L., Smith, Brian J., Milhem, Mohammed
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836085/
https://ncbi.nlm.nih.gov/pubmed/29462961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10020053
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