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Somatic genome alterations in relation to age in lung squamous cell carcinoma

Lung squamous cell carcinoma (LUSC) is the most common cause of global cancer-related mortality and the major risk factors is smoking consumption. By analyzing ∼500 LUSC samples from The Cancer Genome Atlas, we detected a higher mutational burden as well as a higher level of methylation changes in y...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Meucci, Stefano, Keilholz, Ulrich, Heim, Daniel, Klauschen, Frederick, Cacciatore, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6114948/
https://ncbi.nlm.nih.gov/pubmed/30181806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25848
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