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The N-recognin UBR4 of the N-end rule pathway is required for neurogenesis and homeostasis of cell surface proteins
The N-end rule pathway is a proteolytic system in which single N-terminal amino acids of proteins act as a class of degrons (N-degrons) that determine the half-lives of proteins. We have previously identified a family of mammals N-recognins (termed UBR1, UBR2, UBR4/p600, and UBR5/EDD) whose conserve...
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| Publicado no: | PLoS One |
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| Principais autores: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6114712/ https://ncbi.nlm.nih.gov/pubmed/30157281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202260 |
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