AXER is an ATP/ADP exchanger in the membrane of the endoplasmic reticulum

To fulfill its role in protein biogenesis, the endoplasmic reticulum (ER) depends on the Hsp70-type molecular chaperone BiP, which requires a constant ATP supply. However, the carrier that catalyzes ATP uptake into the ER was unknown. Here, we report that our screen of gene expression datasets for m...

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Udgivet i:Nat Commun
Main Authors: Klein, Marie-Christine, Zimmermann, Katharina, Schorr, Stefan, Landini, Martina, Klemens, Patrick A. W., Altensell, Jacqueline, Jung, Martin, Krause, Elmar, Nguyen, Duy, Helms, Volkhard, Rettig, Jens, Fecher-Trost, Claudia, Cavalié, Adolfo, Hoth, Markus, Bogeski, Ivan, Neuhaus, H. Ekkehard, Zimmermann, Richard, Lang, Sven, Haferkamp, Ilka
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6113206/
https://ncbi.nlm.nih.gov/pubmed/30154480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06003-9
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