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An Update on Sec61 Channel Functions, Mechanisms, and Related Diseases

The membrane of the endoplasmic reticulum (ER) of nucleated human cells harbors the protein translocon, which facilitates membrane integration or translocation of almost every newly synthesized polypeptide targeted to organelles of the endo- and exocytotic pathway. The translocon comprises the polyp...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Lang, Sven, Pfeffer, Stefan, Lee, Po-Hsien, Cavalié, Adolfo, Helms, Volkhard, Förster, Friedrich, Zimmermann, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672155/
https://ncbi.nlm.nih.gov/pubmed/29163222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00887
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