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An Update on Sec61 Channel Functions, Mechanisms, and Related Diseases

The membrane of the endoplasmic reticulum (ER) of nucleated human cells harbors the protein translocon, which facilitates membrane integration or translocation of almost every newly synthesized polypeptide targeted to organelles of the endo- and exocytotic pathway. The translocon comprises the polyp...

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Bibliografiske detaljer
Udgivet i:Front Physiol
Main Authors: Lang, Sven, Pfeffer, Stefan, Lee, Po-Hsien, Cavalié, Adolfo, Helms, Volkhard, Förster, Friedrich, Zimmermann, Richard
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672155/
https://ncbi.nlm.nih.gov/pubmed/29163222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00887
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