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Quantitative Proteomics and Differential Protein Abundance Analysis after Depletion of Putative mRNA Receptors in the ER Membrane of Human Cells Identifies Novel Aspects of mRNA Targeting to the ER

In human cells, one-third of all polypeptides enter the secretory pathway at the endoplasmic reticulum (ER). The specificity and efficiency of this process are guaranteed by targeting of mRNAs and/or polypeptides to the ER membrane. Cytosolic SRP and its receptor in the ER membrane facilitate the co...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Bhadra, Pratiti, Schorr, Stefan, Lerner, Monika, Nguyen, Duy, Dudek, Johanna, Förster, Friedrich, Helms, Volkhard, Lang, Sven, Zimmermann, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8230838/
https://ncbi.nlm.nih.gov/pubmed/34208277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26123591
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