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Quantitative Proteomics and Differential Protein Abundance Analysis after Depletion of Putative mRNA Receptors in the ER Membrane of Human Cells Identifies Novel Aspects of mRNA Targeting to the ER

In human cells, one-third of all polypeptides enter the secretory pathway at the endoplasmic reticulum (ER). The specificity and efficiency of this process are guaranteed by targeting of mRNAs and/or polypeptides to the ER membrane. Cytosolic SRP and its receptor in the ER membrane facilitate the co...

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Bibliografische gegevens
Gepubliceerd in:Molecules
Hoofdauteurs: Bhadra, Pratiti, Schorr, Stefan, Lerner, Monika, Nguyen, Duy, Dudek, Johanna, Förster, Friedrich, Helms, Volkhard, Lang, Sven, Zimmermann, Richard
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8230838/
https://ncbi.nlm.nih.gov/pubmed/34208277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26123591
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