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Therapeutic silencing of FSP27 reduces the progression of atherosclerosis in Ldlr(−/−) mice

BACKGROUND AND AIMS: Obesity, hepatosteatosis, and hypertriglyceridemia are components of the metabolic syndrome and independent risk factors for cardiovascular disease. The lipid droplet-associated protein CIDEC (cell death-inducing DFFA-like effector C), known in mice as FSP27 (fat-specific protei...

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Detalhes bibliográficos
Publicado no:Atherosclerosis
Main Authors: Rajamoorthi, Ananthi, Lee, Richard G., Baldán, Ángel
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6113075/
https://ncbi.nlm.nih.gov/pubmed/29859472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2018.05.045
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