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Therapeutic silencing of microRNA-33 inhibits the progression of atherosclerosis in Ldlr(−/−) mice
OBJECTIVE: To study the efficacy of anti-miRNA-33 therapy on the progression of atherosclerosis. APPROACH AND RESULTS: Ldlr(−/−) mice were injected subcutaneously with PBS, control or anti-miR-33 oligonucleotides weekly and fed a Western diet for 12 weeks. At the end of treatment, the expression of...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4157595/ https://ncbi.nlm.nih.gov/pubmed/23702658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.301732 |
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