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Disruption of Planar Cell Polarity Pathway Attributable to Valproic Acid-Induced Congenital Heart Disease through Hdac3 Participation in Mice
BACKGROUND: Valproic acid (VPA) exposure during pregnancy has been proven to contribute to congenital heart disease (CHD). Our previous findings implied that disruption of planar cell polarity (PCP) signaling pathway in cardiomyocytes might be a factor for the cardiac teratogenesis of VPA. In additi...
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Publicado no: | Chin Med J (Engl) |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Medknow Publications & Media Pvt Ltd
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6111683/ https://ncbi.nlm.nih.gov/pubmed/30127218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0366-6999.239311 |
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