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Disruption of planar cell polarity activity leads to developmental biliary defects

Planar cell polarity (PCP) establishes polarity within an epithelial sheet. Defects in PCP are associated with developmental defects involving directional cell growth, including defects in kidney tubule elongation that lead to formation of kidney cysts. Given the strong association between kidney cy...

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Autori principali: Cui, Shuang, Capecci, Louis M., Matthews, Randolph P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045807/
https://ncbi.nlm.nih.gov/pubmed/21215262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.12.041
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