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Loss of a Candidate Biliary Atresia Susceptibility Gene, add3a, Causes Biliary Developmental Defects in Zebrafish

OBJECTIVES: Biliary atresia (BA) is a progressive fibroinflammatory cholangiopathy affecting the bile ducts of neonates. Although BA is the leading indication for pediatric liver transplantation, the etiology remains elusive. Adducin 3 (ADD3) and X-prolyl aminopeptidase 1 (XPNPEP1) are 2 genes previ...

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Dettagli Bibliografici
Pubblicato in:J Pediatr Gastroenterol Nutr
Autori principali: Tang, Vivian, Cofer, Zenobia C., Cui, Shuang, Sapp, Valerie, Loomes, Kathleen M., Matthews, Randolph P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074882/
https://ncbi.nlm.nih.gov/pubmed/27526058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPG.0000000000001375
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