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Analysis of MLN4924 (Pevonedistat) as a Potential Therapeutic Agent in Malignant Melanoma
The NEDD8 pathway is a known activator of the ubiquitin-protease system, a complex partially responsible for the degradation of proteins involved in cell-cycle regulation and neoplastic growth. In this study, we evaluated the anti-tumor potential of MLN4924 (pevonedistat); a potent NEDD8 inhibitor....
Sparad:
| I publikationen: | Melanoma Res |
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| Huvudupphovsmän: | , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2018
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6110958/ https://ncbi.nlm.nih.gov/pubmed/30020196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CMR.0000000000000474 |
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