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Molecular Dynamics Simulations Revealed the Regulation of Ligands to the Interactions between Androgen Receptor and its Coactivator
Androgen receptor (AR) plays important roles in gene expression regulation, sexual phenotype maintenance and prostate cancer (PCa) development. The communications between the AR ligand-binding domain (LBD) and its coactivator are critical to the activation of AR. It is still unclear how the ligand b...
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| Yayımlandı: | J Chem Inf Model |
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| Asıl Yazarlar: | , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6110957/ https://ncbi.nlm.nih.gov/pubmed/29993249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.8b00283 |
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