SLC6A3 Polymorphism Predisposes to Dopamine Overdose in Parkinson's Disease

In Parkinson's disease (PD), cognitive functions mediated by brain regions innervated by ventral tegmental area (VTA) worsen with dopamine replacement therapy, whereas processes relying on regions innervated by the substantia nigra pars compacta (SNc) improve. The SLC6A3 gene encodes the dopami...

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Detalles Bibliográficos
Publicado en:Front Neurol
Main Authors: Robertson, Brian D., Al Jaja, Abdullah S., MacDonald, Alex A., Hiebert, Nole M., Tamjeedi, Ruzbeh, Seergobin, Ken N., Schwarz, Ute I., Kim, Richard B., MacDonald, Penny A.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Neurology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110885/
https://ncbi.nlm.nih.gov/pubmed/30186226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2018.00693
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