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Poly (ADP-ribose) Polymerase Inhibitors in the Management of Ovarian Cancer: A Drug Class Review

OBJECTIVE: To review the pharmacology, safety, efficacy, and role of poly adenosine diphosphate [ADP]-ribose polymerase (PARP) inhibitors in the treatment and maintenance of relapsed, advanced ovarian cancer. SUMMARY: A total of 3 phase 2 trials and 2 phase 3 trials were reviewed that evaluated the...

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Udgivet i:P T
Main Authors: Ringley, J. Tanner, Moore, Donald C., Patel, Jolly, Rose, Maegan S.
Format: Artigo
Sprog:Inglês
Udgivet: MediMedia USA, Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110640/
https://ncbi.nlm.nih.gov/pubmed/30186027
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