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Targeting Mitochondrial Oxidative Stress to Mitigate UV-Induced Skin Damage

Unmitigated UV radiation (UVR) induces skin photoaging and multiple forms of cutaneous carcinoma by complex pathways that include those mediated by UV-induced reactive oxygen species (ROS). Upon UVR exposure, a cascade of events is induced that overwhelms the skin’s natural antioxidant defenses and...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Brand, Rhonda M., Wipf, Peter, Durham, Austin, Epperly, Michael W., Greenberger, Joel S., Falo, Louis D.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110189/
https://ncbi.nlm.nih.gov/pubmed/30177881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00920
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