Identification of novel macropinocytosis inhibitors using a rational screen of Food and Drug Administration‐approved drugs

BACKGROUND AND PURPOSE: Macropinocytosis is involved in many pathologies, including cardiovascular disorders, cancer, allergic diseases, viral and bacterial infections. Unfortunately, the currently available pharmacological inhibitors of macropinocytosis interrupt other endocytic processes and have...

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Dades bibliogràfiques
Publicat a:Br J Pharmacol
Autors principals: Lin, Hui‐Ping, Singla, Bhupesh, Ghoshal, Pushpankur, Faulkner, Jessica L, Cherian‐Shaw, Mary, O'Connor, Paul M, She, Jin‐Xiong, Belin de Chantemele, Eric J, Csányi, Gábor
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109223/
https://ncbi.nlm.nih.gov/pubmed/29953580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14429
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