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PKCδ-Mediated Nox2 Activation Promotes Fluid-Phase Pinocytosis of Antigens by Immature Dendritic Cells

AIMS: Macropinocytosis is a major endocytic pathway by which dendritic cells (DCs) internalize antigens in the periphery. Despite the importance of DCs in the initiation and control of adaptive immune responses, the signaling mechanisms mediating DC macropinocytosis of antigens remain largely unknow...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Singla, Bhupesh, Ghoshal, Pushpankur, Lin, Huiping, Wei, Qingqing, Dong, Zheng, Csányi, Gábor
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879126/
https://ncbi.nlm.nih.gov/pubmed/29632528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00537
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