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Vti1a/b regulate synaptic vesicle and dense core vesicle secretion via protein sorting at the Golgi
The SNAREs Vti1a/1b are implicated in regulated secretion, but their role relative to canonical exocytic SNAREs remains elusive. Here, we show that synaptic vesicle and dense-core vesicle (DCV) secretion is indeed severely impaired in Vti1a/b-deficient neurons. The synaptic levels of proteins that m...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6109172/ https://ncbi.nlm.nih.gov/pubmed/30143604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05699-z |
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