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The evolving role of DNA inter-strand crosslinks in chemotherapy
DNA crosslinking agents make up a broad class of chemotherapy agents that target rapidly dividing cancer cells by disrupting DNA synthesis. These drugs differ widely in both chemical structure and biological effect. In cells, crosslinking agents can form multiple types of DNA lesions with varying ef...
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| Publié dans: | Curr Opin Pharmacol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6108900/ https://ncbi.nlm.nih.gov/pubmed/29679802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2018.04.004 |
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