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p97 Promotes a Conserved Mechanism of Helicase Unloading during DNA Cross-Link Repair

Interstrand cross-links (ICLs) are extremely toxic DNA lesions that create an impassable roadblock to DNA replication. When a replication fork collides with an ICL, it triggers a damage response that promotes multiple DNA processing events required to excise the cross-link from chromatin and resolve...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Fullbright, George, Rycenga, Halley B., Gruber, Jordon D., Long, David T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108885/
https://ncbi.nlm.nih.gov/pubmed/27644328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00434-16
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