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The FANCM/FAAP24 Complex is Required for the DNA Inter-strand Crosslink-Induced Checkpoint Response
Cells from Fanconi anemia (FA) patients are extremely sensitive to DNA inter-strand crosslinking (ICL) agents, but the molecular basis of the hypersensitivity remains to be explored. FANCM (FA complementation group M), and its binding partner, FAAP24, anchor the multi-subunit FA core complex to chro...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2928996/ https://ncbi.nlm.nih.gov/pubmed/20670894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.07.005 |
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