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Efficient genome editing using tRNA promoter-driven CRISPR/Cas9 gRNA in Aspergillus niger
As a powerful tool for fast and precise genome editing, the CRISPR/Cas9 system has been applied in filamentous fungi to improve the efficiency of genome alteration. However, the method of delivering guide RNA (gRNA) remains a bottleneck in performing CRISPR mutagenesis in Aspergillus species. Here w...
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| Udgivet i: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6108506/ https://ncbi.nlm.nih.gov/pubmed/30142205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202868 |
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