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Efficient genome editing using tRNA promoter-driven CRISPR/Cas9 gRNA in Aspergillus niger

As a powerful tool for fast and precise genome editing, the CRISPR/Cas9 system has been applied in filamentous fungi to improve the efficiency of genome alteration. However, the method of delivering guide RNA (gRNA) remains a bottleneck in performing CRISPR mutagenesis in Aspergillus species. Here w...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Song, Letian, Ouedraogo, Jean-Paul, Kolbusz, Magdalena, Nguyen, Thi Truc Minh, Tsang, Adrian
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6108506/
https://ncbi.nlm.nih.gov/pubmed/30142205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202868
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