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[(18)F]Fluoro-hydroxyphenethylguanidines: Efficient Synthesis and Comparison of Two Structural Isomers as Radiotracers of Cardiac Sympathetic Innervation

Fluorine-18 labeled phenethylguanidines are currently under development in our laboratory as radiotracers for quantifying regional cardiac sympathetic nerve density using PET imaging techniques. In this study, we report an efficient synthesis of (18)F-hydroxyphenethylguanidines consisting of nucleop...

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Publicat a:ACS Chem Neurosci
Autors principals: Jung, Yong-Woon, Jang, Keun Sam, Gu, Guie, Koeppe, Robert A., Sherman, Phillip S., Quesada, Carole A., Raffel, David M.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6108090/
https://ncbi.nlm.nih.gov/pubmed/28322043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.7b00051
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