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[(18)F]Fluoro-hydroxyphenethylguanidines: Efficient Synthesis and Comparison of Two Structural Isomers as Radiotracers of Cardiac Sympathetic Innervation

Fluorine-18 labeled phenethylguanidines are currently under development in our laboratory as radiotracers for quantifying regional cardiac sympathetic nerve density using PET imaging techniques. In this study, we report an efficient synthesis of (18)F-hydroxyphenethylguanidines consisting of nucleop...

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Detalhes bibliográficos
Publicado no:ACS Chem Neurosci
Main Authors: Jung, Yong-Woon, Jang, Keun Sam, Gu, Guie, Koeppe, Robert A., Sherman, Phillip S., Quesada, Carole A., Raffel, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6108090/
https://ncbi.nlm.nih.gov/pubmed/28322043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.7b00051
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